Project Description: Long-Lasting Insecticidal Nets (LLINs) are the current first line choice in malaria vector control in sub-Saharan Africa (SSA), with most countries adopting universal coverage campaigns with free or subsidized nets. However, there is only limited knowledge from few countries of the effective life of LLINs under user conditions, an essential parameter for determining the operational and cost-effectiveness of this strategy. This study investigates LLIN effectiveness by measuring attrition, bioefficacy, chemical content and physical degradation in... Long-Lasting Insecticidal Nets (LLINs) are the current first line choice in malaria vector control in sub-Saharan Africa (SSA), with most countries adopting universal coverage campaigns with free or subsidized nets. However, there is only limited knowledge from few countries of the effective life of LLINs under user conditions, an essential parameter for determining the operational and cost-effectiveness of this strategy. This study investigates LLIN effectiveness by measuring attrition, bioefficacy, chemical content and physical degradation in Tanzania. We will use a two-stage approach: Firstly, LLINs from recent net campaigns will be evaluated retrospectively. The sampled households will then be provided with one of three leading LLIN products and followed up for three years in a prospective study to compare the performance of the LLIN brands in vivo. We will also develop a GIS-based network to understand potential spatial reasons for net loss and deterioration; to monitor insecticide resistance and to show malaria incidence data collected from local health centers and national surveys. The IHI is a partner in this project, and will be the main local counterpart in Tanzania from where field collections will be coordinated and where laboratory bioassays will be executed for ABCD component of the project.
Principal Investigator : Sarah Moore
Department Name : EHES
Time frame: (2013-01-01) - (2017-09-30)